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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Int J Parasitol. 2014 Feb 28;44(6):369–379. doi: 10.1016/j.ijpara.2014.01.010

Fig. 5.

Fig. 5

The effect of recombinant Ixodes scapularis serpin (rIxscS-1E1) on platelet aggregation function. Various amounts, of rIxscS-1E1 (as indicated in A-D) were co-incubated with cattle whole blood for 10 min at 37°C as described in Section 2.10. Addition of 20 μM adenosine diphosphate (AD ) or 0.5U/μL of thrombin triggered platelet aggregation. Platelet aggregation was monitored over 8 min using the whole blood platelet aggregometer as described in Section 2.10. (A B) The observed electrical resistance as an index for platelet aggregation. (C, D) The percentage of inhibition of ADP- and thrombin-triggered platelet aggregation, respectively. Experiments were duplicated.