Table 2.
Overview of cohort characteristics in ongoing microbiome studies.
| Cohort | Location | Enrolment | Cohort size | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Europe | North America | Australia | Prospective | FDR | GP | Pregnancy | Birth | Young children | Teen | Screening | Enrolling | T1D cases | |
| DiPP | ✓ | ✓ | ✓ | ✓ | ✓ | 180 000 | 8500 | 300 | |||||
| DIABIMMUNE | ✓ | ✓ | ✓ | ✓ | ✓ | 12 000 | 4400 | 4 | |||||
| TEENDIAB | ✓ | ✓ | ✓ | n.a. | 1500 | ? | |||||||
| ImmunDiabRisk | ✓ | ✓ | ✓ | ✓ | ✓ | n.a. | 200 | ? | |||||
| TEDDY | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | 500 000 | 12 000 | 800 | ||||
| ENDIA | ✓ | ✓ | ✓ | ✓ | n.a. | 1400 | 50 | ||||||
DiPP = Diabetes Prediction and Prevention Project; DIABIMMUNE = Pathogenesis of Type 1 Diabetes – Testing the Hygiene Hypothesis; TEDDY = The Environmental Determinants of Diabetes in the Young study; ENDIA = Environmental Determinants of Islet Autoimmunity; FDR = first-degree relatives; GP = general practitioner; n.a. = not applicable; T1D = type 1 diabetes.