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SEW2871 treatment ameliorated spontaneous colitis in IL-10–/– mice. (a) Myeloperoxidase (MPO) concentration in colon tissues of each group was determined using an enzyme-linked immunosorbent assay (ELISA) kit. (b) The serum amyloid A (SAA) concentration was determined by ELISA. Data are all presented as means ± standard error of the mean (s.e.m.) (n = 6 for each group; *P < 0·05 versus water-treated IL-10–/– controls).
