Fig. 4.
Comparison of anti-dsDNA titres between wild-type and Friend leukaemia virus integration 1 Fli-1+/−) Murphy Roths large (MRL)/lpr mice. Sera were collected from wild-type and Fli-1+/− MRL/lpr mice at the ages of 22–24 weeks. Anti-dsDNA autoantibody titres were determined by enzyme-linked immunosorbent assay (ELISA). Data presented are the mean optical density (OD) 450 ± standard error (s.e.) at 1:100–1:800 dilutions in each group (wild-type MRL/lpr mice, n = 9; Fli-1+/− MRL/lpr mice, n = 6). A single asterisk indicates P < 0·05.