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. 2014 Jun 9;177(1):168–178. doi: 10.1111/cei.12323

Fig. 6.

Fig. 6

T cell frequency (CD3+, CD4+ and CD8+ T cells) was studied from days 30 to 90 of life for each single animal. In diabetic (a) and non-diabetic (b) LEW.1AR1-iddm rats the T cell frequency was unique for each single rat of the LEW.1AR1-iddm strain independent of diabetes development. In the LEW.1AR1 strain, the LEW.1WR1 strain and the LEW strain the T cell frequency was more stable over time compared to the LEW.1AR1-iddm rats (c). In the background strain LEW.1AR1 all animals showed a strain-specific decrease of CD3+ and CD4+ T cells at day 60 of life while the LEW.1WR1 and LEW rats showed only small changes in the T cell frequency over the lifetime (c). (d) = diabetic, (nd) = non-diabetic.