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. 2014 Jun 9;177(1):179–189. doi: 10.1111/cei.12324

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Fig. 5 — Carbachol-induced [Ca²⁺]_i signal in the functional assay using ammonium sulphate (AS)-precipitated immunoglobulins from sera from patients with primary Sjögren's syndrome (pSS), disease controls and healthy controls. Proteins were added 1 h before measurement to the cells. Data are given as percentage of the results without immunoglobulins. Each data-point represents the mean of four independently performed experiments per patient. Bar indicates median value. Comparison was performed using the Mann–Whitney U-test. *P ≤ 0·001 versus patients with pSS. Stimulatory activity was defined as ≥ 130%, inhibitory activity as ≤ 70%. = no effect on receptor activity; SSc = systemic sclerosis; EOMG = early-onset myasthenia gravis; LOMG = late-onset myasthenia gravis.

Inline graphic — Carbachol-induced [Ca²⁺]_i signal in the functional assay using ammonium sulphate (AS)-precipitated immunoglobulins from sera from patients with primary Sjögren's syndrome (pSS), disease controls and healthy controls. Proteins were added 1 h before measurement to the cells. Data are given as percentage of the results without immunoglobulins. Each data-point represents the mean of four independently performed experiments per patient. Bar indicates median value. Comparison was performed using the Mann–Whitney U-test. *P ≤ 0·001 versus patients with pSS. Stimulatory activity was defined as ≥ 130%, inhibitory activity as ≤ 70%. = no effect on receptor activity; SSc = systemic sclerosis; EOMG = early-onset myasthenia gravis; LOMG = late-onset myasthenia gravis.