Table 1.
Strength of association among numbers of leucocytes in peripheral blood and histopathological phenotypes.
| Leucocytes† | Glomerulonephritis (GN) | Crescents | Renal vasculitis |
|---|---|---|---|
| Dendritic cells | 0·376*** | 0·236*** | 0·436*** |
| Granulocytes | 0·393*** | 0·332*** | 0·249*** |
| Macrophages/monocytes | 0·276*** | 0·145** | 0·319*** |
| CD4+ T cells | n.s. | n.s. | 0·248*** |
| CD8+ T cells | n.s. | n.s. | 0·140* |
| CD4−CD8− T cells | 0·285*** | 0·248*** | 0·235*** |
| B cells | n.s. | n.s. | n.s. |
Strength of association expressed as Pearson's correlation coefficients (r) and P-values; *P < 0·01; **P < 0·005; ***P < 0·0001.
†
Numbers of cells in peripheral blood at 12 weeks of age (/μl). n.s. = not significant; GN = percentage of glomeruli with nephritic lesions; crescents = number of crescents in 120 glomeruli; renal vasculitis = number of inflamed vessels in four kidney sections. Three hundred and eighty-three mice underwent both flow cytometry and histological analyses.