Table 3.

Leucocytosis and their susceptibility non-Fas quantitative trait loci (QTLs).

Leucocytosis	QTL	Chromosome and location†	Representative marker	Allele‡	LOD§ (trait)	Variance¶	Candidate gene††
Total DCs, cDCs, granulocytes and macrophages/monocytes	Scg-1	1, 76·25 cM	D1MIT15	ss	6·5 (cDCs)	7%	Fasl, 69·95 cM
Total DCs, cDCs, granulocytes and macrophages/monocytes	Scg-2	1, 51·5 cM	D1MIT387	ss	5·1 (cDCs)	6%	Bcl2, 49·76 cM
pDCs and granulocytes	C17	17, 17·98 cM	D17MIT21	ss	4·5 (granulocyte)	5%	H2, 17·98 cM
							Tnf, 18·59 cM

^†Chromosome and cM location from the Mouse Genome Database (http://www.informatics.jax.org).

^‡Genotypes of mice: s = spontaneous crescentic glomerulonephritis-forming/Kinjoh (SCG/Kj); b = B6.

^§Base-10 logarithm of odds (LOD) score in quantitative trait loci (QTL) analyses by MapManager QTX in free regression model.

^¶Percentage of trait variance calculated by MapManager QTX.

^††cM location from the Mouse Genome Database. DCs = dendritic cells; cDCs = conventional DCs; pDCs = plasmacytoid DCs.