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A cartoon diagram showing the unliganded form of Vc-SiaP (in the absence of Neu5Ac) and the ligand-bound form of Fn-SiaP in the presence of Neu5Ac. All structural figures were produced using PyMOL (Schrödinger). The structures are coloured as a gradient from blue to red, with the N-terminus in blue. The figure clearly shows the closure of the domains around the bound ligand (Neu5Ac), which is shown in ball-and-stick representation.
