Table 2.

Summary of significant clusters from voxel-wise CVRi comparisons

Cluster	Anatomic label	Voxels	Max intensity x, y, z (mm)	Maximum t-score
NC versus AD
1	Precuneus	7744	—6, 61, 20	5.42
2	Thalamus	3648	14,—7, 16	4.97
3	Medial temporal lobe	2048	26, 5, —24	3.82
4	Thalamus	2048	14,21, 16	4.97
5	Thalamus	1792	—10, 37, 20	4.18
6	Caudate	1664	—14, —19,4	4.96
7	Inferior parietal	1664	34, 41, 40	3.50
8	Medial temporal lobe	1536	26, 13, —8	3.83
9	Superior temporal	1536	—50, 17, 8	4.18
10	Posterior cingulate	1344	10,41,44	3.68
11	Parietal	1344	30, 13, 60	3.62
MCI versus AD
1	Thalamus/Caudate	1984	18, 9, 24	5.1697
2	Thalamus/Precuneus	1536	—10, 37, 20	3.4937

(r = 0.45, p = 0.001) (Fig. 2C), which remained significant after controlling for all covariates, ΔR² = 0.09, β = 0.37, p = 0.02.