Table 2. α-Smooth muscle actin, macrophages, and lymphocytes in kidney specimens from Nx rats and the controls, which received BMmSCs or hAFSCs.
α-SMA (%) | M (cell/mm2) | Lymphocytes (cell/mm2) | |
---|---|---|---|
Sham | 0.3±0.1 | 17±3 | 13±3 |
Sham+BMmSCs | 0.5±0.2 | 19±3 | 20±5 |
Sham+hAFSCs | 0.1±0.0 | 9±4 | 67±16a,b |
Nx | 6.3±0.7a,b,c | 50±8a,b,c | 33±2 |
Nx+BMmSCs | 2.7±0.4d | 35±2 | 25±2 |
Nx+hAFSCs | 0.3±0.1d,e | 18±3d | 70±8a,b,e |
Abbreviations: α-SMA, α-smooth muscle actin; BMmSCs, bone marrow mesenchymal stem cells; hAFSCs, human amniotic fluid stem cells; M, macrophages; Nx, 5/6 nephrectomy model.
aP<0.01 versus sham.
bP<0.01 versus sham+BMmSCs.
cP<0.001 versus sham+hAFSCs.
dP<0.001versus Nx.
eP<0.05versus Nx+BMmSCs.