Table 1. Changes in circulating MBD marker levels during 3 years of follow-up.
|
Intact PTH |
Phosphorus |
Calcium |
||||
|---|---|---|---|---|---|---|
| Visit number (time period) | Median (pg/ml) | Percentage of achievement of target | Mean (s.d.) (mg/dl) | Percentage of achievement of target | Mean (s.d.) (mg/dl) | Percentage of achievement of target |
| 0 (up to Dec 2007) | 265 | 14.5 | 5.53 (1.37) | 63.3 | 9.45 (0.88) | 65.5 |
| 1 (Jan 2008 to Mar 2008) | 259 | 21.7 | 5.57 (1.39) | 61.9 | 9.45 (0.85) | 68.6 |
| 2 (Apr 2008 to Jun 2008) | 225 | 30.8 | 5.49 (1.35) | 65.2 | 9.49 (0.83) | 69.5 |
| 3 (Jul 2008 to Sep 2008) | 187 | 38.6 | 5.34 (1.37) | 65.7 | 9.58 (0.82) | 67.5 |
| 4 (Oct 2008 to Dec 2008) | 189 | 38.2 | 5.41 (1.38) | 65.6 | 9.55 (0.79) | 69.4 |
| 5 (Jan 2009 to Mar 2009) | 191 | 37.6 | 5.56 (1.41) | 62.1 | 9.46 (0.80) | 72.1 |
| 6 (Apr 2009 to Jun 2009) | 172 | 42.3 | 5.44 (1.36) | 64.4 | 9.51 (0.78) | 70.8 |
| 7 (Jul 2009 to Sep 2009) | 160 | 45.0 | 5.27 (1.37) | 67.1 | 9.56 (0.81) | 68.5 |
| 8 (Oct 2009 to Dec 2009) | 172 | 40.9 | 5.39 (1.39) | 65.0 | 9.51 (0.77) | 71.4 |
| 9 (Jan 2010 to Mar 2010) | 173 | 41.6 | 5.52 (1.37) | 63.7 | 9.47 (0.75) | 73.6 |
| 1 0 (Apr 2010 to Jun 2010) | 165 | 42.5 | 5.47 (1.36) | 65.3 | 9.50 (0.76) | 73.1 |
| 11 (Jul 2010 to Sep 2010) | 150 | 46.1 | 5.24 (1.34) | 69.1 | 9.58 (0.77) | 71.0 |
| 12 (Oct 2010 to Dec 2010) | 160 | 44.1 | 5.32 (1.36) | 67.7 | 9.52 (0.74) | 73.5 |
Abbreviations: MBD, mineral and bone disorder; PTH, parathyroid hormone.
Target levels of serum calcium, phosphorus, and intact PTH were defined as 8.4–10.0 mg/dl, 3.5–6.0 mg/dl, and 60–180 pg/ml, respectively.