Table 2.
List of the 6 selected genes/proteins implicated in ‘Semaphorin signaling in neurons’ summarizing the spot number, differential expression ratios, sequence coverage, subcellular localization, and molecular functions.
IDENTIFIER | PROTEIN NAME | SPOT NUMBER | P10/P30 ± STDEV | A/P30 ± STDEV | P10/A ± STDEV | SEQUENCE COVERAGE (%) | SUBCELLULAR LOCALIZATION | MOLECULAR FUNCTIONS |
---|---|---|---|---|---|---|---|---|
COF1_MOUSE | Cofilin 1. non-Muscle | 2220 | 1.98 ± 0.35 | 2.16 ± 0.42 | 74 | 0005737: cytoplasm; 0044464: cell part; 0031252: cell leading edge; 0042995: cell projection; 0016020: membrane; 0005856: cytoskeleton; 0005634: nucleus | 0005515: protein binding | |
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DPYL1_MOUSE | Collapsin Response Mediator Protein 1 | 789 | 2.39 ± 0.55 | 2.41 ± 0.57 | 31 | 0043005: neuron projection; 0005737: cytoplasm; 0005856: cytoskeleton; 0043025: neuronal cell body; 0043234: protein complex | 0016787: hydrolase activity; 0005515: protein binding | |
802 | 3.39 ± 1.3 | 4.5 ± 1.72 | 35 | |||||
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DPYL2_MOUSE | Collapsin Response Mediator Protein 2 | 527 | 5.71 ± 0.37 | 8.4 ± 1.08 | 33 | 0043005: neuron projection; 0005737: cytoplasm; 0005739: mitochondrion; 0043234: protein complex; 0043025: neuronal cell body; 0030427: site of polarized growth | 0016787: hydrolase activity; 0005515: protein binding | |
533 | 4.18 ± 0.45 | 5.55 ± 0.44 | 3 | |||||
545 | 2.54 ± 0.64 | 3.74 ± 0.97 | 31 | |||||
549 | 1.64 ± 0.29 | 40 | ||||||
562 | 4.29 ± 0.38 | 5.37 ± 0.62 | 53 | |||||
585 | 3.59 ± 0.72 | −1.53 ± 0.05 | 5.5 ± 1.1 | 52 | ||||
589 | 2.5 ± 0.25 | 3.19 ± 0.51 | 41 | |||||
685 | 2.3 ± 0.28 | −1.51 ± 0.05 | 3.46 ± 0.38 | 8 | ||||
705 | 1.8 ± 0.3 | 2.08 ± 0.35 | 63 | |||||
721 | 1.85 ± 0.2 | 59 | ||||||
731 | 1.45 ± 0.13 | 71 | ||||||
743 | 1.89 ± 0.29 | 63 | ||||||
664 | 2.36 ± 0.35 | 3.19 ± 0.33 | 47 | |||||
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DPYL4_MOUSE | Collapsin Response Mediator Protein 3 | 790 | 2.25 ± 0.21 | −1.7 ± 0.06 | 3.83 ± 0.42 | 53 | 0005737: cytoplasm | 0016787: hydrolase activity; 0005515: protein binding |
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DPYL3_MOUSE | Collapsin Response Mediator Protein 4 | 664 | 2.36 ± 0.35 | 3.19 ± 0.33 | 30 | 0005737: cytoplasm; 0031252: cell leading edge; 0042995: cell projection; 0005856: cytoskeleton; 0043234: protein complex; 0031982: vesicle; 0043231: intracellular membrane-bounded organelle; 0005576: extracellular region; 0030427: site of polarized growth; 0043005: neuron projection; 0044464: cell part | 0016787: hydrolase activity; 0005515: protein binding; 0043167: ion binding | |
729 | −1.87 ± 0.09 | −1.62 ± 0.09 | 37 | |||||
784 | 3.97 ± 0.85 | −2.6 ± 0.04 | 10.33 ± 2.34 | 50 | ||||
787 | 6.6 ± 1.53 | −6.18 ± 0.01 | 40.74 ± 9.87 | 46 | ||||
810 | 6.9 ± 1.38 | −2.83 ± 0.06 | 19.56 ± 4.95 | 24 | ||||
814 | 2.95 ± 0.38 | −1.71 ± 0.06 | 5.06 ± 0.78 | 45 | ||||
823 | 7.83 ± 2.25 | 10.18 ± 3.45 | 19 | |||||
834 | 3.8 ± 0.8 | −1.76 ± 0.07 | 6.66 ± 1.4 | 50 | ||||
800 | 5.86 ± 0.59 | −2.87 ± 0.04 | 16.85 ± 2.19 | 44 | ||||
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DPYL5_MOUSE | Collapsin Response Mediator Protein 5 | 782 | 2.73 ± 0.8 | 4.78 ± 1.29 | 62 | 0043005: neuron projection; 0005737: cytoplasm; 0043025: neuronal cell body | 0016787: hydrolase activity; 0005515: protein binding |