Table 4.
Unadjusted and adjusted HR for predictors of MACE after wait listing.
| Variable | Unadjusted hazard ratio |
Adjusted hazard ratioa | ||
|---|---|---|---|---|
| P value | HR (95% CI) | P value | HR (95% CI) | |
| Patient characteristics | ||||
| Highrisk | 0.004 | 8.16 (1.97–33.79) | ||
| Age | <0.001 | 1.05 (1.03–1.08) | 0.003 | 1.05 (1.02–1.08) |
| Previous transplantation | 0.694 | 1.16 (0.55–2.43) | ||
| Smoking | 0.021 | 2.10 (1.12–3.93) | ||
| Gender | 0.335 | 1.41 (0.70–2.80) | ||
| Diabetes | 0.002 | 2.61 (1.41–4.85) | ||
| History of CAD | <0.001 | 4.32 (2.30–8.08) | 0.042 | 2.09 (1.03–4.24) |
| History of CVD | <0.001 | 4.94 (2.07–11.77) | 0.018 | 2.96 (1.20–7.31) |
| History of PVD | <0.001 | 4.20 (2.13–8.28) | ||
| BMI (kg/m2) | 0.153 | 0.95 (0.88–1.02) | ||
| Time on dialysis before wait listing | 0.001 | 1.01 (1.00-1.01) | 0.004 | 1.01 (1.00-1.01) |
|
| ||||
| Screening/intervention | ||||
| LV hypertrophy | 0.735 | 0.87 (0.38–2.00) | ||
| Positive stress test (28 of 154 conclusive stress tests) | 0.018 | 2.79 (1.19–6.53) | ||
| Significant coronary artery stenosis (38 of 58 coronary angiographies) | 0.039 | 1.49 (1.02–2.17) | ||
| Coronary intervention (PCI or CABG; 18 of 58 coronary angiographies) | 0.202 | 1.78 (0.74–4.29) | ||
aFinal model determined by Cox regression with stepwise selection.
CAD: coronary artery disease; CVD: cerebrovascular disease; PVD: peripheral vascular disease; LV hypertrophy: left ventricular hypertrophy; BMI: body mass index.