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Bryonolic acid (BA) (1) induces Nrf2 and its target genes. RAW 264.7 cells were treated with BA at different time points. qRT-PCR was performed probing for Nrf2 and Nrf2 target genes including catalase (CAT), glutamate-cysteine ligase catalytic subunit (GCLC), glutathione reductase (GR), heme oxygenase-1 (HO-1) and NAD(P)H dehydrogenase, quinone 1 (NQO1) at varying time points in cells treated with 100 μM BA.
