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. 2014 Jun 19;2014:263674. doi: 10.1155/2014/263674

Table 7.

Findings on new falciparum infections detected by day 28.

Study name Study groups with number of new infections Risk (R) Risk ratio (RR) (95% CI) P value Interpretation for the RR values
Sawa et al., 2013 [34] DP (n/N): 0/137 
AL (n/N): 8/147
0.00 
0.054
0.063 
(0.004–1.083)
0.057 There has been 37% reduction in new infections associated with DP treatment but reduction is not statistically significant.

Yavo et al., 2011 [33] DP (n/N): 1/191 
AL (n/N): 3/183
0.005 
0.016
0.319 
(0.034–3.042)
0.321 There was a 68% reduction in new infections in favour of DP treatment but result not statistically significant.

Bassat et al., 2009 [32] DP (n/N): 27/1038 
AL (n/N): 64/510
0.026 
0.125
0.207 
(0.134–0.321)
<0.001 This result shows 79% reduction in incidence of new falciparum infections in favour of DP treatment and the reduction is statistically significant. The lowest plausible reduction is 67.9% while the highest is 86.6% as defined by the 95% CI of the RR.

Mens et al., 2008 [31] DP (n/N): 0/67 
AL (n/N): 1/67
0.000 
0.015
0.333 
(0.014–8.039)
0.499 DP treatment was associated with a 66.7% reduction in risk for a patient to acquire new infections compared to AL. The reduction is not statistically significant.