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. Author manuscript; available in PMC: 2014 Jul 9.
Published in final edited form as: Nano Lett. 2010 Nov 22;10(12):4920–4928. doi: 10.1021/nl102889y

Figure 1.

Figure 1

Characterization of multifunctional nanocomplexes. (a) Schematic representation of antibody and PEG conjugation to nanocomplexes. (b) Fluorescence (FL) intensity of nanocomplexes at 830 nm compared with standard unenhanced ICG showing ∼50-fold enhancement by nanocomplexes. Inset: Near-IR FL image of vials with enhanced ICG (nanocomplexes) and standard ICG of equivalent concentration. (c) T2-weighted MR images of nanocomplexes in aqueous media at various concentrations. The [Fe] concentration in each sample is provided at the bottom of the respective images. (d) Spin-spin relaxation rate (T2−1) as a function of [Fe] of the nanocomplexes. Optical image of nanocomplexes (e) dispersed in aqueous media and (f) with magnet (shown with arrow).