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. Author manuscript; available in PMC: 2014 Jul 9.
Published in final edited form as: Twin Res Hum Genet. 2014 Apr 15;17(3):183–191. doi: 10.1017/thg.2014.22

Table 4. Associations of Methylation Levels of the LY86 Gene With Body Mass Index and Additional Indices for Adiposity in the Third Panel (N = 703) Representing the General Population of Youth.

CpG sitesa BMI % body fat VATb SAATb




Partial correlationc p Partial correlationc p Partial correlationc p Partial correlationc p
LY86_1 .131 <.001 .138 <.001 .147 .002 .130 .006
LY86_2 .100 .008 .097 .01 .151 .001 .137 .004
LY86_3 .089 .02 .090 .02 .120 .01 .105 .03
LY86_4 .094 .01 .087 .02 .126 .008 .094 .05
LY86_5 .088 .02 .093 .01 .137 .004 .097 .04
LY86_6 .067 .08 .077 .04 .127 .008 .085 .08
LY86_pc1d .096 .01 .099 .009 .138 .004 .109 .02

Note: BMI = body mass index; VAT = visceral adipose tissue; SAAT = subcutaneous abdominal adipose tissue;

a

Adjusted for batch;

b

Log-transformed;

c

Adjusted for age, gender, and race;

d

The first principal component score calculated based on the methylation levels of six CpG sites, adjusted for batch.