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(A) Necrosis assessed by trypan blue staining following SI/RO in primary adult rat cardiomyocytes demonstrating a decrease with Na2S treatment compared to control. AntagomiR-21 not only blocked the protective effect of Na2S, but also exacerbated necrosis. (B) Representative TUNEL staining reflecting apoptosis in primary adult rat cardiomyocytes showing a decrease with Na2S treatment compared to control. AntagomiR-21 abolished the anti-apoptotic effect of Na2S.
