Table 4.
Relationship between MMP-9, -11, and -15 expression and tumor characteristics
| Characteristics | MMP-9 | MMP-11 | MMP-15 |
|---|---|---|---|
| ER status | |||
| Positive | 3.343 | 5.036 | 0.588 |
| Negative | 4.362 | 4.795 | 0.851 |
| P-value | <0.0001 | 0.0322 | <0.0001 |
| Tumor size (cm) | |||
| ≤2 | 3.613 | 5.046 | 0.609 |
| >2 | 3.654 | 4.907 | 0.650 |
| P-value | NS | NS | 0.032 |
| Tumor grade | |||
| 1–2 | 3.217 | 4.919 | 0.571 |
| 3 | 4.081 | 5.024 | 0.703 |
| P-value | <0.0001 | NS | <0.0001 |
| Nodal status | |||
| Negative | 3.583 | 4.898 | 0.624 |
| Positive | 3.682 | 5.038 | 0.647 |
| P-value | NS | NS | NS |
| PAM50 subtype | |||
| Basal | 4.674 | 4.375 | 0.655 |
| Other | 3.375 | 5.066 | 0.631 |
| P-value | <0.0001 | <0.0001 | 0.044 |
Note: Bold indicates significance P<0.05.
Abbreviations: NS, not significant; MMP, matrix metalloproteinases; ER, estrogen receptor.