Table 6.
Relationship between ADAM-8 and -17 expression and tumor characteristics
| Characteristics | ADAM-8 | ADAM-17 |
|---|---|---|
| ER status | ||
| Positive | 0.942 | 1.815 |
| Negative | 1.225 | 2.165 |
| P-value | <0.0001 | <0.0001 |
| Tumor size (cm) | ||
| ≤2 | 0.999 | 1.860 |
| >2 | 1.060 | 1.921 |
| P-value | 0.045 | NS |
| Tumor grade | ||
| 1–2 | 0.906 | 1.818 |
| 3 | 1.147 | 2.007 |
| P-value | <0.0001 | <0.0001 |
| Nodal status | ||
| Negative | 1.011 | 1.856 |
| Positive | 1.051 | 1.936 |
| P-value | NS | 0.019 |
| PAM50 subtype | ||
| Basal | 1.304 | 2.205 |
| Other | 0.952 | 1.825 |
| P-value | <0.0001 | <0.0001 |
Note: Bold indicates significance P<0.05.
Abbreviations: NS, not significant; ER, estrogen receptor.