Table 2.

Adjusted multivariate models for the nested case-control and sensitivity case-cohort analyses comparing HIV-1 transmission for subtype C versus non-C subtypes

	Nested case-control				Case-Cohort
	Odds ratio (95%CI) adjusted for gender, age and unprotected sex		Odds ratio (95%CI) adjusted gender age, unprotected sex plus plasma HIV-1 RNA		Hazard ratio (95%CI) adjusted for gender, age and unprotected sex		Hazard ratio (95%CI) adjusted gender age, unprotected sex plus plasma HIV-1 RNA
	env	gag	env	gag	env	gag	env	gag
C vs. non-C	1.14 (0.74–1.75) p=0.6	0.98 (0.63.1.52) p=0.9	1.18 (0.76–1.83) p=0.5	1.03 (0.66–1.60) p=0.9	1.56 (0.89–2.76) p=0.1	0.92 (0.51–1.67) p=0.8	1.58 (0.86–2.90) p=0.1	0.97 (0.52–1.80) p=0.9
C vs. A	1.17 (0.74–1.84) p=0.5	1.09 (0.68–1.75) p=0.7	1.25 (0.78–1.99) p=0.3	1.13 (0.70–1.84) p=0.6	1.22 (0.65–2.29) p=0.5	0.88 (0.45–1.72) p=0.7	1.26 (0.65–2.44) p=0.5	0.91 (0.45–1.83) p=0.8
C vs. D	1.39 (0.76–2.56) p=0.3	1.79 (0.93–3.47) p=0.08	1.27 (0.68–2.38) p=0.5	1.60 (0.82–3.13) p=0.2	2.19 (0.95–5.06) p=0.07	1.29 (0.49–3.37) p=0.6	2.29 (0.95–5.51) p=0.07	1.28 (0.45–3.62) p=0.6

Adjusted for gender and age of HIV-1 infected partner

Unprotected sex and plasma HIV-1 RNA assessed at baseline in nested case-control model and longtitudinally for case-cohort model