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. Author manuscript; available in PMC: 2014 Jul 9.
Published in final edited form as: Circ J. 2012 Jul 30;76(8):1811–1818. doi: 10.1253/circj.cj-12-0801

Figure 1.

Figure 1

Leukocyte recruitment at site vascular injury with endothelial denudation and platelet deposition. Sequential adhesion cascade of leukocyte attachment to and transmigration across surface-adherent platelets involves the initial tethering and rolling of leukocytes on platelet P-selectin and is followed by firm leukocyte adhesion and transplatelet migration, processes that are dependent on leukocyte Mac-1 and platelet receptors, including GPIbα, JAM-3, and fibrinogen bound to GPIIb/IIIa.