Skip to main content
. 2014 Jul 9;9(7):e101728. doi: 10.1371/journal.pone.0101728

Table 3. Stratified Analysis of dairy products or milk Intake and gastric cancer Risk.

Group NO. of studies OR(95%CI) Q statistic P value I2 value(%)
Total Dairy products 26 1.09(0.96–1.25) 105.22 <0.001 76.2
Design
Cohort 8 1.01(0.91–1.13) 7.13 0.416 1.8
Case-control 18 1.10(0.92–1.30) 95.42 <0.001 82.2
Hospital based 9 0.86(0.72–1.02) 12.19 0.143 34.4
Population based 9 1.36(1.07–1.74) 63.26 <0.001 87.4
Geographic area
Asia 10 1.09(0.86–1.38) 72.34 <0.001 87.6
Europe 7 0.91(0.76–1.08) 6.63 0.356 9.6
North America 7 1.18(1.01–1.38) 8.73 0.189 31.3
South America 2 1.45(0.54–3.89) 9.14 0.003 89.1
Lauren's classification
Diffuse 4 1.04(0.87–1.24) 2.58 0.461 0
Intestinal 4 1.13(0.79–1.62) 9.15 0.027 67.2
Location
Cardia 3 1.32(0.84–2.08) 25.74 <0.001 92.2
Noncardia 3 1.21(0.95–1.54) 10.98 0.004 81.8
Gender
Men 9 1.04(0.96–1.13) 13.19 0.587 0
Women 8 1.02(0.95–1.09) 10.59 0.751 0
Adjustment for confounders
Alcohol Yes 7 1.18(0.96–1.25) 10.65 0.1 43.6
No 19 1.18(0.98–1.42) 92.75 <0.001 80.6
Smoking Yes 15 1.10(0.96–1.25) 27.34 0.017 48.8
No 11 1.07(0.83–1.39) 77.73 <0.001 87.1
BMI Yes 5 1.13(1.01–1.26) 1.71 0.798 0
No 21 1.09(0.93–1.29) 102.92 <0.001 80.6
Total energy intake Yes 10 1.22(1.02–1.46) 22.83 0.007 60.6
No 16 1.01(0.83–1.23) 82.11 <0.001 81.7
H. pylori infection Yes 2 1.43(0.65–3.15) 6.46 0.011 84.5
No 24 1.08(0.93–1.25) 98 <0.001 76.5
Publication year
Before 2000 9 1.10(0.90–1.34) 18.83 0.016 57.4
After 2000 17 1.08(0.91–1.29) 86.30 <0.001 81.5
Quality score
<7 stars 8 1.11(0.75–1.65) 65.81 <0.001 89.4
≥7 stars 18 1.05(0.95–1.16) 28.70 0.037 40.8
Fermented(Yes vs. No)
Non-Fermented 13 1.10(0.92–1.32) 30.68 0.01 51.1
Fermented 8 0.94(0.81–1.08) 15.42 0.42 2.7
Milk
Asia 5 0.90(0.75–1.08) 7.64 0.501 0
Europe 5 1.57(1.01–2.44) 8.71 0.126 51.8
North America 3 1.68(0.90–3.14) 4.15 0.069 54.1
Hawaii 2 1.11(0.85–1.44) 0.45 0.106 47.6
Cheese
Asia 3 1.05(0.72–1.54) 0.35 0.840 0
Europe 4 0.75(0.52–1.08) 9.19 0.027 67.4

Non-Fermented: milk; Fermented: cheese, yogurt, sour milk;