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. Author manuscript; available in PMC: 2014 Jul 9.
Published in final edited form as: Am J Clin Pathol. 2012 Jan;137(1):75–85. doi: 10.1309/AJCPMMLQ67YOMGEW

Table 1. Discriminative values on test set.

MCL is considered as positive and SLL as negative.

TPa TNb FPc FNd Sensitivitye Specificityf Accuracyg
graphic file with name nihms595110t1.jpg CD20/CD23 ratio 30 40 0 0 100%h 100% 100%
FMC7/CD23 ratio 30 37 3 0 100% 92% 96%
CD20/CD11c ratio 24 33 7 6 80% 82% 81%
Combined Ratio Score 30 37 3 0 100% 92% 96%
graphic file with name nihms595110t2.jpg CD23 intensity 30 35 5 0 100% 88% 93%
FMC7 intensity 24 32 8 6 80% 80% 80%
CD20 intensity 24 33 7 6 80% 82% 81%
Light chain 18 38 2 12 60% 95% 80%
CD5 intensity 19 22 18 11 63% 55% 59%
a

TP (true positive) = the number of MCL cases which are diagnosed correctly

b

TN (true negative) = the number of SLL cases which are diagnosed correctly

c

FP (false positive) = the number of SLL cases which are diagnosed as MCL wrongly

d

FN (false negative) = the number of MCL cases which are diagnosed as SLL wrongly

e

Sensitivity to MCL is the portion of MCL cases that are correctly diagnosed by a feature (TP/(TP+FN)).

f

Specificity is the portion of SLL cases that are diagnosed correctly (TN/(TN+FP)).

g

Accuracy is the portion of all correctly diagnosed cases.

h

Performance higher than 95% is shown in boldface.