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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2014 Apr 30;13(7):1942–1951. doi: 10.1158/1535-7163.MCT-13-1000

Fig. 1. Endogenous LEF-1 and miR-26b expression among colon cancer cell lines.

Fig. 1

A, B) Relative expression of miR-26b and LEF-1, c-Myc mRNA reveals endogenous miR-26b and LEF-1,c-Myc transcripts in a non-cancer colon epithelial cell line (CCD 841 CoN) and colon cancer cell lines DLD-1, SW480 and Colo 320. miR-26b expression is inversely correlated with LEF-1 and c-Myc expression. C) Western blot of LEF-1 expression in HEK 293 and colon cell lysates. The colon cancer cells express multiple LEF-1 isoforms. The relative protein levels were consistent with mRNA levels. D) miR-26b expression in human colon cancer tissue and normal tissue obtained from NCBI gene expression Omnibus database. * p-value < 0.05; ** p-value < 0.01; *** p-value < 0.005.