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Selected ongoing clinical trials of drugs targeting Hedgehog signaling in prostate cancer, adapted from clinicaltrials.gov
| Target | Agent | Phase | Summary | Identifier |
|---|---|---|---|---|
| Smoothened (SMO) | Itraconazole | II | Single-arm efficacy study; Itraconazole in docetaxel-refractory metastatic CRPC |
NCT01450683 |
| Smoothened (SMO) | Itraconazole | II | Single-arm efficacy study; Itraconazole in PSA-recurrent/non-metastatic prostate cancer |
NCT01787331 |
