Table 3.

Fatty acid changes in normal-appearing and infiltrating ductal carcinoma explants induced by the stearoyl CoA desaturase 1 inhibitor CAY10566

Explants were incubated with CAY10566 (1.0 µM) for 48 hours. Lipid extracts were prepared and analyzed by gas liquid chromatography for a comprehensive fatty acid profile. Values are expressed as means±SD of three independent determinations.

IDC=infiltrating ductal carcinoma; SFA=saturated fatty acids; MUFA=monounsaturated fatty acids; PUFA=polyunsaturated fatty acids.

^*p<0.05 (CAY10566 treated vs. untreated explant).