Table 2. Effect of capsule and SeM protein on survival of Streptococcus equi in equine blood and in neutrophils suspended in equine serum.
Strain | Phenotype | Median % Survival (Range) |
|
---|---|---|---|
Blood (n=18) | Neutrophil Suspension (n=18) |
||
CF32 | HA+, SeM+ | 14.0 (7.0–20.0) | 14.0 (6.0–35.0) |
SF463 | |||
Lex90 | HA–, SeM+ | 6.0 (3.0–9.0) | 4.0 (1.0–8.0) |
Lex93 | P=0.00096a | P=0.0002a | |
Se 1-8 | HA+, SeM– | 4.0 (1.0–8.0) | 2.0 (1.0–7.0) |
Se19 | P=0.09b | P=0.019b |
Percentages were calculated from triplicate data from 9 separate experiments for each Se strain. a, P values calculated using Wilcoxon’s signed rank test of significance of difference in survival between HA+ SeM+ and HA– SeM+ strains. P values for the comparison of HA+ SeM+ and HA+ SeM– were also 0.00096 (blood) and 0.0002 (neutrophils). b, P values calculated as above for differences in % survival between HA– SeM+ and HA+ SeM– strains. Survival of Se1-8 and Se19 was significantly greater (P=0.019) in blood than in neutrophils.