Table 3.
The daily released amount of amoxicillin measured with either replacing the solvent daily or replenishing the solvent. There were significant differences in the 1st and 2nd day with the different methods.
| Released drug (mg/day) | Amoxicillin solvent replenishment |
Amoxicillin cumulative release |
|---|---|---|
| Mean ± SEM | Mean ± SEM | |
| Day 1∗∗ | 0.260 ± 0.037 | 0.168 ± 0.030 |
| Day 2∗∗∗ | 0.202 ± 0.026 | 0.098 ± 0.005 |
| Day 3 | 0.081 ± 0.015 | 0.085 ± 0.016 |
| Day 4 | 0.049 ± 0.013 | 0.063 ± 0.009 |
| Day 5 | 0.032 ± 0.012 | 0.042 ± 0.012 |
| Day 6 | 0.007 ± 0.002 | 0.021 ± 0.015 |
| Day 7 | 0.003 | 0.001 ± 0.001 |
| Day 8 | 0.003 | 0.002 |
**is the difference between the released drug on the first day with the two different methods, and ∗∗∗ is the difference between the released drug on the second day with the two different methods.