Table 1. Effects of quinones on the amyloidogenecity of insulin.
| Lag time (h) | T50 (h) | Maximum intensity[2] | |
|---|---|---|---|
| INS[1] | 4.52 ± 0.45 | 8.17 ± 0.85 | 1.04 ± 0.05 |
| INS + BQ | N.D.[3] | N.D. | 0.19 ± 0.04 |
| INS + NQ | N.D. | N.D. | 0.12 ± 0.02 |
| INS + AQ | 4.51 ± 0.23 | 7.83 ± 1.03 | 0.63 ± 0.04 |
| INS + PQ | 6.97 ± 0.48 | 13.00 ± 0.82 | 0.77 ± 0.06 |
| INS + CP | 5.01 ± 0.32 | 8.50 ± 0.41 | 0.50 ± 0.09 |
| INS + EM | 4.73 ± 0.27 | 8.67 ± 0.94 | 0.42 ± 0.05 |
| INS + AE | 4.67 ± 0.54 | 9.67 ± 1.70 | 0.50 ± 0.19 |
| INS + RH | 4.75 ± 0.43 | 9.45 ± 0.43 | 0.64 ± 0.10 |
[1]The concentration of insulin was 100 μM and all assays were repeated three times.
[2]The maximum fluorescence intensity of insulin was set as 1.
[3]N.D., the lag time and T50 were too long to be accurately determined during the test.