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. 2014 Jul 10;4:5643. doi: 10.1038/srep05643

Table 4. Database Scan results using various homology detection methods for Target Dataset.

    OCRS PSI-BLAST HMMER HHpred FASTA search
Fold Class and Title #Fold #Hits EFF #Hits EFF #Hits EFF #Hits EFF #Hits EFF
All beta Proteins                      
GFP-like protein 273 273 100 216 79 228 84 263 96 248 91
Cupredoxin-like proteins 120 117* 98 110 92 108 90 106 88 103 86
Acid Proteases 578 485 84 480 83 462 80 472 82 514 89
Ribosomal Protein L14 291 260 87 123 42 210 72 234 80 221 76
Alpha and beta (α + β) Proteins                      
β-Grasp (Ubiquitin-like) protein 400 363 90 265 66 156 39 327 82 304 76
Nucleoside Triphosphate Hydrolase 530 492 93 370 70 369 70 508 96 514 97
RNAase A-like proteins 319 312 98 251 79 289 91 310 97 299 94
Cysteine Proteinases 198 170 86 132 66 144 73 164 83 172 87
Alpha and beta (α/β) Proteins                      
50 S Ribosomal Protein L25 111 111* 100 74 66 74 67 107 96 100 90
50 S Ribosomal Protein L6P 317 282 89 155 49 212 67 264 82 285 90
Difydrofolate reductase-like proteins 272 248 91 216 79 238 88 237 87 242 89
Pyruvate kinase N-terminal domain 65 61 94 46 71 48 74 63 97 60 93

Here, table lists the total number of identified protein homolog during the fold scan against the PDB and the fold detection efficiencies of each method. Here #hits indicates structural fold detected by each method and EFF indicates the fold detection efficiency. Fold detection efficiency is calculated as the ratio of total true positive hits to the total number of structural folds in the PDB.

*Fold detection results for Cupredoxin-like proteins and 50S Ribosomal Protein L25 are obtained using the OCR-fingerprint.