Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 10;5:323. doi: 10.3389/fimmu.2014.00323

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Aretz, Wamhoff, Hanske, Heymann and Rademacher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Sequence alignment and consensus structure of CTLRs. (A) The dendrogram depicts the hierarchical clustering of CRDs based on a structure-based multiple sequence alignment. The two major branches are termed cluster A and B. Pairwise sequence similarities and RMSDs of C_α atoms are shown in matrix format. (B) Key structural features of the CTLD fold are mapped on the predicted consensus structures (top). The peptide backbone is displayed as a continuous line and colored according to RMSD of C_α atoms. The CRD of DC-SIGN (PDB code: 2XR6) is shown for comparison (bottom). The ribbon representation is colored according to secondary structure elements (red: α-helices; yellow: β-strands; blue: loop regions).