Figure 2.

Forest plots of the effect of ESAs on QoL end points assessed by scales and subscales of the FACT questionnaire. Each solid square represents the SMD between groups for individual trials, and the size of the square represents the weight of the individual study in the meta-analysis. Horizontal lines indicate 95% CIs. The dashed vertical lines indicate the thresholds for clinical important differences for FACT-F (⩾3) and FACT-An (⩾4). The width of the diamond shows the 95% CI for the pooled SMD. Trials are sorted by weight. Confidential data are masked.