Table 1. Baseline characteristics of study participants.
Usual care control group (CON), n=15 | Resistance training group (INT), n=15 | Healthy reference group (REF), n=19 | |
---|---|---|---|
Age, years (s.d.) |
35.8 (8.9) |
34.4 (7.6) |
31.5 (6.0) |
Body mass index, kg m−2 (s.d.) |
24.2 (3.2) |
24.0 (3.7) |
24.2 (5.0) |
Smoking | |||
Current smoker, no. (%) | 2 (13%) | 0 (0%) | 3 (16%) |
Former smoker, no. (%) |
5 (33%) |
5 (33%) |
9 (47%) |
Physical activity level | |||
Sedentarya, no. (%) |
8 (53%) |
7 (47%) |
11 (58%) |
Diagnosis | |||
Seminoma, no. (%) | 7 (47%) | 7 (47%) | NA |
Non-seminoma, no. (%) |
8 (53%) |
8 (53%) |
NA |
Elevated tumour-markers, no. (%) |
8 (53%) |
7 (47%) |
NA |
Elevated AFP, no. (%) | 4 (27%) | 3 (20%) | NA |
Elevated HCG, no. (%) |
8 (53%) |
6 (40%) |
NA |
Orchiectomy | |||
Days from surgery, median (interquartile range) | 130 (35–336) | 185 (78–1618) | NA |
Bilateralb, no. (%) | 1 (7%) | 2 (13%) | NA |
Unilateral, no. (%) |
14 (93%) |
13 (87%) |
NA |
Gonadal status, serum | |||
Testosterone, nmol l−1 | 17.0 (4.9) | 18.8 (6.5) | NA |
FSH, IU l−1 | 9.0 (12.6) | 6.4 (7.3) | NA |
LH, IU l−1 | 4.3 (3.6) | 2.2 (1.9) | NA |
Abbreviations: AFP=alfa-phetoprotein; FSH=follicle-stimulating hormone; HCG=human chorionic gonadotropin beta-chains; LH=luteinizing hormone; NA=not available.
Continuous variables are reported as mean (s.d.) and categorical variables are reported as numbers (%). There were no significant differences between groups (P>0.05).
‘Sedentary' is defined as ‘performing less than 150 min of moderate intensity physical activity per week'.
Standard management of patients with bilateral orchiectomy includes testosterone substitution, but none of the patients included in this study had testosterone levels outside of the normal range at the point of inclusion.