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. 2014 Jun 3;111(1):149–156. doi: 10.1038/bjc.2014.286

Table 2. Reported tumour-associated endothelial markers (TEM).

Marker Cell surface expression on tumour endothelium References
CD54 (ICAM-1)
Downregulated in renal cell carcinoma
(Griffioen et al, 1996)
CD105 (endoglin)
Upregulated in breast, colon, cervix, lung, prostate and brain tumours
(Duff et al, 2003; Minhajat et al, 2006)
CD109
Upregulated in breast, colon and lung carcinoma
(Seaman et al, 2007)
CD137 (4-1BB)
Upregulated in colon and lung carcinoma
(Broll et al, 2001; Seaman et al, 2007)
CXCR7
Upregulated in renal cell carcinoma and meningioma
(Wurth et al, 2011; Maishi et al, 2012)
CD276 (B7-H3) Upregulated in breast, colon, lung, renal carcinoma and Glioblastoma (Seaman et al, 2007; Lemke et al, 2012; Qin et al, 2013)