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. 2014 May 22;109(4):416. doi: 10.1007/s00395-014-0416-y

Fig. 1.

Fig. 1

Time course and dose response of Ang II effects on the LC3-II to LC3-I ratio, expression of beclin-1 and SQSMT1/p62 by VSMCs. Time course (a) and dose response (d) of Ang II effects on the LC3-II to LC3-I ratio, top representative blots of LC3-II and LC3-I after treatment with Ang II, bottom densitometry analysis of the ratio of LC3-II to LC3-I. Time course (b) and dose response (e) of Ang II on beclin-1 expression, top representative blots of beclin-1 and GAPDH after treatment with Ang II, bottom densitometry analysis of beclin-1. Time course (c), and dose response (f) of Ang II on SQSMT1/p62 expressions, top representative blots of SQSMT1/p62 and GAPDH after treatment with Ang II, bottom densitometry analysis of SQSMT1/p62 and GAPDH. Ang II (10−7 mol/L) stimulates for 6, 12, 24, 48 and 72 h. Ang II (10−9–10−5 mol/L) stimulates for 24 h. Control group is expressed as 1. Data are presented as mean ± SEM (n = 4–6). *p < 0.05 vs. control