Fig. 9.

Effects of Ang II (10⁻⁷ mol/L) on rapamycin (Rap, 10 mg/L)-induced increase in LC3-II, increase in beclin-1 and decrease in SQSMT1/p62 expression. a Effects of Ang II on Rap-induced increase in the LC3-II to LC3-I ratio, top representative blots of LC3-II and LC3-I expression after treatment with Ang II, bottom densitometry analysis of the LC3-II to LC3-I ratio. b Effects of Ang II on Rap-induced increase of beclin-1 expression, top representative blots of beclin-1 and GAPDH expression after treatment with Ang II, bottom densitometry analysis of beclin-1 and GAPDH expression. c Effects of Ang II on Rap-induced decrease in SQSMT1/p62 expression, top representative blots of SQSMT1/p62 and GAPDH expression after treatment with Ang II, bottom densitometry analysis of SQSMT1/p62 and GAPDH expression. The control group is expressed as 1. Data are presented as mean ± SEM (n = 6–8). *p < 0.05 vs. control. ^† p < 0.05 vs. Ang II, and Rap