Fig. 2.
Genomic differences between ovarian tumors from obese versus non-obese KpB mice reveal alterations in metabolically relevant genes. Heat map representation of 131 genes found to be significantly up- or down-regulated in the ovarian tumors from the obese versus non-obese KpB mice (FDR < 0.1). Many metabolically relevant genes, such as lipocalin, fatty acid amide hydrolase, ectonucleoside triphosphate diphosphohydrolase, fatty acid 2-hydroxylase, glycerol-3-phosphate acyltransferase, protein phosphatase, protein kinase C and AMP deaminase 3, were upregulated in obese tumors.