Table 3. Association between ACE genetic polymorphisms with hypertension and noise in the studied subjects.
Genes | Groups | Hypertensive (99) | Normotensive (279) | OR, 95% CI (HT versus NT‡) | |
ACE G2350A polymorphism | AA | Control | 8 | 54 | Reference |
Exposed | 12 | 46 | 1.761 (0.663–4.679) | ||
GA | Control | 1 | 14 | Reference | |
Exposed | 20 | 26 | 10.70* (1.305–88.906) | ||
GG | Control | 18 | 66 | Reference | |
Exposed | 40 | 73 | 2.01* (1.05–3.842) | ||
ACE I/D polymorphism | ID | Control | 3 | 9 | Reference |
Exposed | 18 | 26 | 2.077 (0.423–8.751) | ||
DD | Control | 24 | 125 | Reference | |
Exposed | 54 | 119 | 2.363† (1.374–4.066) | ||
Total | Control | 27 | 134 | Reference | |
Exposed | 72 | 145 | 2.464† (1.493–4.067) |
Note: *Significance P<0.05.
†Significance P<0.001.
‡HT versus NT: hypertensive versus normotensive.