Table 6.
Average cortical thickness of imaged participants in mm
| Region | PME
|
PTE
|
||||||
|---|---|---|---|---|---|---|---|---|
| non-PME (n = 15) | PME (n = 20) | t value | p1 | non-PTE (n = 9) | PTE (n = 26) | t value | p1 | |
| DLPFC – left | 3.06 (0.18) | 3.00 (0.24) | –0.16 | 0.876 | 3.07 (0.22) | 3.01 (0.22) | –0.56 | 0.580 |
| Rostral middle frontal – left | 3.07 (0.23) | 3.00 (0.27) | –0.64 | 0.528 | 3.05 (0.26) | 3.02 (0.26) | –0.05 | 0.959 |
| Caudal middle frontal – left | 3.02 (0.18) | 3.01 (0.21) | 1.44 | 0.162 | 3.10 (0.16) | 2.99 (0.20) | –1.99 | 0.058 |
| DLPFC – right | 2.94 (0.22) | 2.96 (0.29) | 1.05 | 0.305 | 2.99 (0.28) | 2.94 (0.26) | –0.71 | 0.484 |
| Rostral middle frontal – right | 2.93 (0.24) | 2.94 (0.31) | 0.95 | 0.352 | 2.97 (0.30) | 2.93 (0.28) | –0.67 | 0.508 |
| Caudal middle frontal – right | 2.99 (0.22) | 3.00 (0.30) | 0.98 | 0.336 | 3.03 (0.27) | 2.98 (0.27) | –0.57 | 0.572 |
| Cingulate gyrus – left | 3.67 (0.23) | 3.61 (0.30) | 0.36 | 0.719 | 3.73 (0.20) | 3.61 (0.29) | –1.36 | 0.186 |
| Rostral anterior cingulate – left | 3.86 (0.29) | 3.79 (0.34) | 0.35 | 0.727 | 3.90 (0.20) | 3.79 (0.35) | –1.26 | 0.220 |
| Caudal anterior cingulate – left | 3.47 (0.28) | 3.44 (0.36) | 0.31 | 0.757 | 3.54 (0.33) | 3.42 (0.32) | –1.02 | 0.318 |
| Cingulate gyrus – right | 3.55 (0.24) | 3.54 (0.20) | 0.08 | 0.934 | 3.57 (0.26) | 3.53 (0.20) | –0.35 | 0.729 |
| Rostral anterior cingulate – right | 3.87 (0.33) | 3.83 (0.37) | 0.65 | 0.520 | 3.94 (0.26) | 3.82 (0.37) | –1.59 | 0.125 |
| Caudal anterior cingulate – right | 3.32 (0.35) | 3.35 (0.21) | –0.44 | 0.667 | 3.31 (0.37) | 3.34 (0.24) | 0.96 | 0.344 |
| OFC – left | 3.35 (0.22) | 3.40 (0.24) | 1.78 | 0.086 | 3.42 (0.23) | 3.36 (0.24) | –1.23 | 0.230 |
| Lateral OFC – left | 3.43 (0.23) | 3.41 (0.26) | 1.28 | 0.210 | 3.52 (0.23) | 3.38 (0.24) | –1.60 | 0.123 |
| Medial OFC – left | 3.24 (0.25) | 3.38 (0.29) | 2.02 | 0.054 | 3.28 (0.24) | 3.34 (0.29) | –0.30 | 0.768 |
| OFC – right | 3.34 (0.18) | 3.38 (0.38) | 1.45 | 0.160 | 3.44 (0.27) | 3.33 (0.32) | –1.57 | 0.128 |
| Lateral OFC – right | 3.35 (0.19) | 3.43 (0.35) | 1.95 | 0.062 | 3.46 (0.27) | 3.37 (0.30) | –1.57 | 0.128 |
| Medial OFC – right | 3.32 (0.24) | 3.30 (0.49) | 0.62 | 0.538 | 3.42 (0.28) | 3.27 (0.43) | –1.23 | 0.231 |
| Posterior cingulate – left | 3.14 (0.15) | 3.26 (0.17) | 1.32 | 0.200 | 3.17 (0.14) | 3.22 (0.18) | 0.03 | 0.975 |
| Posterior cingulate – right | 3.06 (0.15) | 3.14 (0.16) | 1.17 | 0.253 | 3.11 (0.18) | 3.10 (0.15) | –0.22 | 0.825 |
| Inferior parietal lobule – left | 3.16 (0.19) | 3.16 (0.21) | 1.22 | 0.233 | 3.26 (0.11) | 3.13 (0.21) | –1.56 | 0.131 |
| Inferior parietal cortex – left | 3.18 (0.22) | 3.15 (0.26) | 0.95 | 0.349 | 3.29 (0.18) | 3.12 (0.25) | –1.59 | 0.125 |
| Supramarginal gyrus – left | 3.15 (0.19) | 3.18 (0.19) | 1.43 | 0.166 | 3.24 (0.10) | 3.14 (0.21) | –1.34 | 0.192 |
| Inferior parietal lobule – right | 3.05 (0.28) | 3.04 (0.30) | 1.34 | 0.192 | 3.20 (0.24) | 2.99 (0.29) | –1.39 | 0.175 |
| Inferior parietal cortex – right | 3.16 (0.24) | 3.10 (0.26) | 0.37 | 0.714 | 3.24 (0.20) | 3.08 (0.25) | –0.59 | 0.561 |
| Supramarginal gyrus – right | 2.91 (0.37) | 2.96 (0.39) | 1.94 | 0.063 | 3.13 (0.32) | 2.87 (0.38) | –1.81 | 0.082 |
| Superior temporal gyrus – left | 3.17 (0.26) | 3.15 (0.22) | 0.78 | 0.440 | 3.30 (0.16) | 3.11 (0.24) | –1.90 | 0.069 |
| Superior temporal gyrus – right | 3.13 (0.36) | 3.08 (0.31) | 0.76 | 0.452 | 3.29 (0.26) | 3.03 (0.32) | –1.65 | 0.112 |
| Post. asp. sup. temporal sulcus – left | 2.99 (0.26) | 2.91 (0.25) | 0.12 | 0.905 | 3.13 (0.19) | 2.88 (0.25) | –0.99 | 0.332 |
| Post. asp. sup. temporal sulcus – right | 3.11 (0.42) | 2.99 (0.37) | 0.99 | 0.332 | 3.37 (0.32) | 2.93 (0.35) | –2.40 | 0.024* |
| Lingual gyrus – left | 2.40 (0.24) | 2.39 (0.19) | 0.38 | 0.709 | 2.48 (0.27) | 2.36 (0.18) | –0.90 | 0.375 |
| Lingual gyrus – right | 2.44 (0.26) | 2.51 (0.19) | 1.35 | 0.187 | 2.54 (0.27) | 2.46 (0.20) | –1.53 | 0.138 |
| Inferior temporal gyrus – left | 3.27 (0.27) | 3.20 (0.32) | 0.62 | 0.543 | 3.40 (0.22) | 3.17 (0.30) | –1.58 | 0.125 |
| Inferior temporal gyrus – right | 3.29 (0.28) | 3.17 (0.37) | 0.24 | 0.810 | 3.40 (0.31) | 3.16 (0.32) | –1.11 | 0.279 |
| Lateral occipital cortex – left | 2.59 (0.23) | 2.57 (0.18) | 0.79 | 0.436 | 2.70 (0.22) | 2.54 (0.18) | –1.86 | 0.074 |
| Lateral occipital cortex – right | 2.70 (0.19) | 2.69 (0.17) | 1.27 | 0.214 | 2.79 (0.20) | 2.67 (0.16) | –2.13 | 0.043 |
| Middle temporal gyrus – left | 3.44 (0.28) | 3.27 (0.31) | –0.13 | 0.899 | 3.58 (0.20) | 3.26 (0.29) | –1.73 | 0.095 |
| Middle temporal gyrus – right | 3.28 (0.37) | 3.25 (0.45) | 1.20 | 0.241 | 3.52 (0.23) | 3.17 (0.43) | –1.79 | 0.085 |
| Parahippocampal gyrus – left | 2.76 (0.35) | 2.96 (0.36) | 1.07 | 0.296 | 2.77 (0.27) | 2.92 (0.39) | 1.48 | 0.150 |
| Parahippocampal gyrus – right | 2.84 (0.24) | 2.84 (0.34) | 0.22 | 0.831 | 2.91 (0.12) | 2.81 (0.33) | 0.26 | 0.798 |
| Inferior frontal gyrus – left | 3.20 (0.19) | 3.17 (0.21) | 0.34 | 0.735 | 3.26 (0.19) | 3.16 (0.20) | –1.17 | 0.252 |
| Pars opercularis gyrus – left | 3.13 (0.19) | 3.13 (0.23) | 0.87 | 0.393 | 3.19 (0.19) | 3.11 (0.22) | –1.07 | 0.294 |
| Pars triangularis gyrus – left | 3.16 (0.28) | 3.09 (0.24) | 0.45 | 0.656 | 3.22 (0.32) | 3.08 (0.23) | –1.42 | 0.169 |
| Pars orbitalis gyrus – left | 3.47 (0.33) | 3.51 (0.35) | 0.27 | 0.792 | 3.55 (0.32) | 3.48 (0.35) | 0.11 | 0.916 |
| Inferior frontal gyrus – right | 3.08 (0.23) | 3.10 (0.33) | 1.47 | 0.153 | 3.21 (0.22) | 3.06 (0.30) | –1.59 | 0.124 |
| Pars opercularis gyrus – right | 3.06 (0.23) | 3.05 (0.31) | 1.54 | 0.136 | 3.19 (0.18) | 3.01 (0.29) | –1.58 | 0.126 |
| Pars triangularis gyrus – right | 2.99 (0.26) | 3.03 (0.34) | 1.60 | 0.122 | 3.13 (0.26) | 2.98 (0.31) | –1.60 | 0.121 |
| Pars orbitalis gyrus – right | 3.34 (0.36) | 3.37 (0.47) | 1.02 | 0.318 | 3.42 (0.44) | 3.34 (0.41) | –0.89 | 0.384 |
| Precuneus cortex – left | 3.02 (0.19) | 3.01 (0.19) | 1.08 | 0.290 | 3.06 (0.20) | 3.00 (0.19) | –1.07 | 0.297 |
| Precuneus cortex – right | 2.99 (0.18) | 2.98 (0.16) | 0.50 | 0.622 | 3.03 (0.13) | 2.97 (0.17) | –0.59 | 0.561 |
| Precentral gyrus – left | 2.80 (0.11) | 2.80 (0.20) | 0.92 | 0.364 | 2.81 (0.13) | 2.80 (0.18) | –0.49 | 0.625 |
| Precentral gyrus – right | 2.68 (0.19) | 2.74 (0.27) | 1.41 | 0.171 | 2.76 (0.23) | 2.70 (0.24) | –0.68 | 0.501 |
| Superior frontal gyrus – left | 3.50 (0.18) | 3.52 (0.28) | 1.47 | 0.153 | 3.51 (0.21) | 3.51 (0.26) | –0.90 | 0.377 |
| Superior frontal gyrus – right | 3.40 (0.15) | 3.45 (0.28) | 0.89 | 0.383 | 3.43 (0.13) | 3.43 (0.26) | –0.02 | 0.982 |
| Superior parietal cortex – left | 2.86 (0.20) | 2.80 (0.13) | 0.00 | 0.998 | 2.91 (0.18) | 2.79 (0.15) | –0.82 | 0.417 |
| Superior parietal cortex – right | 2.83 (0.20) | 2.81 (0.15) | 0.19 | 0.848 | 2.87 (0.18) | 2.80 (0.16) | –0.32 | 0.753 |
| Frontal pole – left | 3.67 (0.52) | 3.55 (0.65) | 0.05 | 0.963 | 3.52 (0.50) | 3.63 (0.63) | 0.49 | 0.628 |
| Frontal pole – right | 3.57 (0.60) | 3.63 (0.60) | –0.03 | 0.973 | 3.55 (0.67) | 3.63 (0.57) | 0.39 | 0.700 |
Values in parentheses are SD. Post. asp. sup. = Posterior aspect of the superior.
1
Adjusted for prenatal MA (or TOB), marijuana, age at time of scan, gender, handedness and pulse sequence.
*
p ≤ 0.099 after multiplicity adjustment within domain category using the step-up Hochberg Bonferroni method [60].