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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Mod Pathol. 2013 Jul 26;27(2):262–270. doi: 10.1038/modpathol.2013.146

Table 3.

Sensitivity, specificity, positive, and negative predictive values for pancreatic and lung adenocarcinomas

Sensitivity (%) Specificity (%) PPV (%) NPV (%)
Mucious PDAC metastases
KRAS mutation 80 54 53 81
 CK20 + 65 72 77 59
 CDX2 + 63 94 94 63
Mucinous lung primaries
KRAS G12C 39 95 88 62
 TTF-1 + 76 96 94 83
 Napsin A + 33 100 100 81
KRAS mutated lung primaries
KRAS G12C 44 96 96 41
KRAS mutated PDAC
KRAS G12R 15 99 86 74

Abbreviations: NPV, negative predictive value; PDAC, pancreatic ductal adenocarcinoma; PPV, positive predictive value.