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. 2014 Apr 29;3:e28611. doi: 10.4161/onci.28611

Table 1. T-cell responses induced by Prostvac.

Test Result Comment
Generation of PSA-specific T cells 56.7% (59/104) with ≥ 2-fold increase post-vaccine Examined 28 d after last vaccine (after expected peak response)
Median magnitude (fold) increase in PSA-specific immune response among responders 5-fold Level of PSA-specific T cells in responders (30/106 PBMC) similar to level of influenza-specific T cells in same patients.
Evidence of antigen spreading (a.k.a. antigen cascade) 67.9% (19/28) Immune response post-vaccine to tumor-associated antigens not in vaccine.