Table 2.
Adjusted ORs for outcomes associated with admission to either tertiary or high-volume neonatal care at the hospital of birth using a ‘standard’ logistic regression model
| Tertiary neonatal unit |
High-volume neonatal unit† |
|||||
|---|---|---|---|---|---|---|
| Outcome | (1) ≤32+6 weeks |
(2) ≤26+6 weeks |
(3) 27+0–32+6 weeks |
(4) ≤32+6 weeks |
(5) ≤26+6 weeks |
(6) 27+0–32+6 weeks |
| Neonatal mortality | 0.77 (0.59 to 1.00) | 0.65* (0.46 to 0.91) | 0.92 (0.69 to 1.22) | 0.73* (0.56 to 0.95) | 0.62** (0.44 to 0.87) | 0.86 (0.65 to 1.14) |
| Any in-hospital mortality | 0.91 (0.72 to 1.15) | 0.78 (0.57 to 1.06) | 1.06 (0.83 to 1.36) | 0.83 (0.65 to 1.05) | 0.71* (0.52 to 0.97) | 0.96 (0.75 to 1.24) |
| BPD | 1.23** (1.07 to 1.40) | 1.50** (1.11 to 2.01) | 1.17 (0.99 to 1.39) | 1.11 (0.97 to 1.28) | 1.59** (1.18 to 2.14) | 1.02 (0.86 to 1.22) |
| Treatment for ROP | 1.26 (0.91 to 1.75) | 1.09 (0.76 to 1.57) | 1.52 (0.91 to 2.55) | 0.95 (0.68 to 1.32) | 0.81 (0.56 to 1.17) | 1.22 (0.71 to 2.09) |
| Surgery for NEC | 1.05 (0.76 to 1.44) | 0.89 (0.58 to 1.36) | 1.17 (0.80 to 1.70) | 1.05 (0.76 to 1.45) | 0.94 (0.62 to 1.45) | 1.11 (0.76 to 1.61) |
| PMA at discharge >40 weeks | 1.17 (0.97 to 1.41) | 1.09 (0.87 to 1.37) | 1.19 (0.97 to 1.47) | 1.13 (0.94 to 1.37) | 1.11 (0.89 to 1.38) | 1.11 (0.90 to 1.37) |
Values are ORs (95% CI).
Models are adjusted for gestational age, gestational age squared, birthweight z-score, use of antenatal steroids, gender, infant year of birth and deprivation.
*p<0.05, **p<0.01, ***p<0.001.
†High volume was defined as being in the top quartile of units by number of care days provided to infants born at ≤32+6 weeks gestation.
BPD, bronchopulmonary dysplasia; NEC, necrotising enterocolitis; PMA, postmenstrual age; ROP, retinopathy of prematurity.