Table 1. The SAGA chromatin modifying complex is highly conserved. Members of the SAGA complex from Human, Drosophila melanogaster, and Saccharomyces cerevisiae are listed along with their approximate molecular mass.
| SAGA chromatin modifying complex members | |||||
|---|---|---|---|---|---|
| Human | Molecular Mass (kDa) | D. melanogaster | Molecular Mass (kDa) | S. cerevisiae | Molecular Mass (kDa) |
| Gcn5/PCAF | 92.1 | Gcn5 (Pcaf) | 92.2 | Gcn5 | 51.1 |
| ADA2B | 46.2 | Ada2B (isoform B) | 62 | Ada2 | 50.5 |
| ADA3 | 47.5 | Ada3 (diskette) | 59.9 | Ada3 | 79.2 |
| SGF29 | 32.2 | Sgf29 | 37.1 | Sgf29 | 29.3 |
| SPT7L | 45.5 | Spt7 | 39.5 | Spt7 | 152.6 |
| ADA1 | 36.9 | Ada1 (Ada 1–2) | 35.4 | Ada1 | 54.4 |
| SPT3 | 34.9 | Spt3 | 43.5 | Spt3 | 38.8 |
| X | X | X | X | Spt8 | 66.1 |
| p38IP | 85.7 | Spt20 | 176.7–201 | Ada5/Spt20 | 67.7 |
| TRRAP | 421.3 | Tra1 (Nipped-A) | 436.00 | Tra1 | 433.1 |
| TAF9 | 29 | TAF9 (enhancer of yellow 1) | 29.3 | Taf9 | 17.3 |
| TAF10 | 24 | TAF10b (TBP-associated factor 10b) | 15.8 | Taf10 | 23 |
| TAF12 | 17.7 | TAF12 (TBP-associated factor 12-D) | 17.6 | Taf12 | 61 |
| X | X | WDA (will decrease acetylation) | 83.7 | X | X |
| TAF5L | 64.8 | X | X | Taf5 | 88.9 |
| SAP130 | 115.3 | X | X | X | X |
| TAF6L | 68.4 | SAF6 | 79.3 | Taf6 | 57.9 |
| USP22 | 56.4 | Nonstop | 56.4 | Ubp8 | 53.6 |
| ATXN7L3 | 38.2 | Sgf11 | 21.3 | Sgf11 | 11.2 |
| ENY2 | 11.1 | E(y)2 (enhancer of yellow 2) | 11.5 | Sus1 | 11.1 |
| ATXN7 | 98.1 | Ataxin-7 | 104.2 | Sgf73 | 72.9 |