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. 2014 Jul 3;4(7):e005122. doi: 10.1136/bmjopen-2014-005122

Figure 3.

Figure 3

Summary of sensitivity (PPA) and specificity (NPA) by expert clinical diagnosis—mean of blind reads. (A) ITD population—summary results calculated across all studies and readers at baseline. DLB is calculated based on probable DLB versus non-DLB. Total is calculated based on SDDD present versus SDDD absent. (B) ITD population—DLB at month 12 calculated for all readers in study PDT301. PS at month 18 and 36 calculated for all readers in study PDT304. (C) PP population—summary results calculated across all studies and readers at baseline. DLB is calculated based on probable DLB versus non-DLB. Total is calculated based on SDDD present versus SDDD absent. (D) PP population—DLB at month 12 calculated for all readers in study PDT301. PS at month 18 and 36 calculated for all readers in study PDT304. DLB, dementia with Lewy bodies; ITD, intent to diagnose; NPA, negative per cent agreement; PP, per protocol; PPA, positive per cent agreement; PS, parkinsonian syndrome; SDDD, striatal dopaminergic deficit disorder.