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. 2013 Oct 15;8(12):e26669. doi: 10.4161/psb.26669

Table 1. Main features of NMCP proteins and lamins. Similar characteristics are denoted in blue and different ones in red.

  NMCPs lamins
Types NMCP1 (monocots 1; dicots 2­‒3 genes)
NMCP2 (1 gene)
B-type (invertebrates 1; vertebrates 2­‒3 genes)
A-type (1 gene in vertebrates and in few invertebrates)
Structure Central coiled-coil rod domain, head and tail
Rod domain flanked by cdk1 sites
NLS in the tail domain
Central coiled-coil rod domain, head and tail
Rod domain flanked by cdk1 sites
NLS in the tail domain
Conserved regions Extremes of the rod domain, linkers and C-terminus Extremes of the rod domain, linkers and C-terminus
Polimerization state Predicted to dimerize Dimerize and form filaments
MW Variable (70-200 kDa) 65-74 kDa
pI Acidic Acidic (B-type lamins); neutral (A-type)
Solubility NSK component NSK component
Subcellular localization Lamina, nucleoplasm Lamina, nucleoplasm
Functions Nuclear shape and size
Chromatin organization (?) (decreased number of chromocenters but the distribution of heterochromatic regions not changed)
Not involved in light induced nuclear movement
Nuclear shape and architecture
Chromatin organization and positioning
Connecting NSK and CSK
DNA replication, repair and transcription
Cell proliferation and differentiation
Genes Min. 2 in most plants Min. 3 in vertebrates, 1 in most invertebrates
Where? Multicellular land plants Metazoan