| Animal p53 |
Arabidopsis SOG1 |
| Functions |
| Transcription factor |
Transcription factor (NAC protein) |
| Activates transcriptional response |
Activates transcriptional response |
| Involved in cell-cycle arrest |
Involved in cell-cycle arrest |
| Stimulates apoptosis |
Stimulates programmed cell death |
| Required for genome stability |
Required for genome stability |
|
Mechanisms of regulation (in response to DNA damage) |
| Phosphorylated by ATM, ATR and CHK1/2 |
Phosphorylated via ATM |
| p53 is stabilized |
The amount of SOG1 does not change |
