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. Author manuscript; available in PMC: 2014 Jul 10.
Published in final edited form as: Adv Pharmacol. 2013;68:421–444. doi: 10.1016/B978-0-12-411512-5.00020-8

Figure 3.

Figure 3

Four hypothetical schemes illustrating how differential coupling between peptide synthesis and release could be enabled either at the pre-motor network or intracellular signal transduction levels. A) Synthesis and release are independently controlled by different inputs. B) Synthesis and release are increased by one input through pERK1/2’s ability to activate both processes. C) Synthesis and release are increased by a third indirect input that controls the two direct inputs, each of which operates independent of the other and pERK1/2. D) Synthesis and release are increased by a third direct input that operates independent of the two others. The third input directly controls pERK1/2 and thereby synthesis and release.