1Table 1.
EAE Incidence | Disease Phenotype |
Incidence | |
---|---|---|---|
WT | 44/47 (93%) | Pure Conventional | 31/44 (71%) |
Pure Atypical | 4/44 (9%) | ||
Mixed | 9/44 (20%) | ||
IFNγRKO | 38/48 (79%) | Pure Conventional | 4/38 (10%) |
Pure Atypical | 24/38 (63%) | ||
Mixed | 10/38 (27%) |
5×106 MOG35–55-reactive, Th1-polarized CD4 T cells were purified and transferred into WT and IFNγRKO recipients (as described in the materials and methods). Data were pooled from at least 6 experiments.